Clinical Features, Management and Maternal-Infant Prognosis in Patients with Complete Uterine Rupture in the Second and Third Trimester of Pregnancy.

Objectives: Our study aimed to investigate the clinical features, management, and maternal-infant prognosis in patients with complete uterine rupture in the second and third trimester of pregnancy. Methods: A total of 15 patients with complete uterine rupture in their second and third trimester of pregnancy who were admitted to our hospital between January 2012 and December 2020 were included in our study. The patients enrolled were divided into the scar group (11 patients) and the non-scar group (4 patients) according to the existence or absence of a uterine scar. The general data, clinical characteristics and follow-up results in the 2 groups were compared. Results: There was no significant difference in age, pregnancy duration or delivery cycle between the 2 groups (P > .05). The incidence of original scar rupture in the scar group was significantly higher than in the non-scar group (P > .05). No significant difference was found in clinical characteristics between the scar and the non-scar groups (P > .05). The most common clinical features included abdominal pain, inability to lie flat, hemorrhagic shock, prenatal vaginal bleeding and uterine rupture, mostly occurring in the lower segments of the uterus and cervix. A total of 3 patients were misdiagnosed as having surgical disease. After completing relevant examinations, the uterine rupture was repaired surgically; the patients were discharged after blood transfusion, and their condition resolved. In all, 3 patients in the non-scar group and 1 patient in the scar group were transferred to the intensive care unit (ICU). All 15 patients were discharged after treatment. Follow-up was completed by all patients for 12 to 36 months, with an average follow-up time of 23.09 ± 2.19 months. Of the 15 patients, 2 underwent induced abortion after 24 months due to unplanned pregnancy. A 5-minute Apgar score of ≤7 in the scar group was higher than that in the non-scar group, but the difference was not statistically significant (P > .05). Perinatal mortality in the 15 patients was 40.00% (6/15). Conclusion: The most common clinical features in patients with complete uterine rupture in the second and third trimester of pregnancy included abdominal pain, inability to lie flat, hemorrhagic shock, prenatal vaginal bleeding and uterine rupture, mostly occurring in the lower segments of the uterus and cervix. In addition, a remarkably worse maternal-infant prognosis was seen in patients with complete uterine rupture in the second and third trimester of scarless pregnancy compared with patients with complete uterine rupture in the second and third trimester of scarred pregnancy.

Preventing deaths due to haemorrhage.

Prevention of deaths from obstetric haemorrhage requires effective health systems including family planning, commodities, personnel, infrastructure and ultimately universal access to comprehensive obstetric care for women giving birth. The main causes of death associated with antepartum haemorrhage are placental abruption, placenta praevia and uterine rupture. Preventive measures include preconceptual folate supplementation, management of hypertensive disorders, early diagnosis of placenta praevia and use of uterine stimulants cautiously, particularly misoprostol. Preventive measures for post-partum haemorrhage include routine active management of the third stage of labour. Treatment involves a cascade of increasingly invasive interventions in rapid sequence until the bleeding is stopped. These interventions include fluid resuscitation, removal of the placenta, bimanual uterine compression, uterotonics, tranexamic acid, suturing of lower genital tract injury, blood product replacement, balloon tamponade, laparotomy, stepwise uterine devascularization, uterine compression sutures and hysterectomy. Emergency temporizing measures include application of the non-pneumatic anti-shock garment, and at laparotomy, aortic compression and uterine tourniquet application. The effectiveness of treatment methods and the optimal dosage of misoprostol are research priorities. Interesting new approaches include transvaginal uterine artery clamping and suction uterine tamponade.

Congenital Uterine Anomalies and Uterine Rupture.

Congenital uterine anomalies are more common than previously recognized. While many women will have no symptoms or problems, some women with congenital uterine anomalies have increased risks of adverse outcomes during pregnancy. This article presents a case study of a woman with a congenital uterine anomaly leading to spontaneous rupture of her unscarred uterus remote from term. The most common types of congenital uterine anomalies and their associated reproductive risks are reviewed. Evaluation of congenital uterine anomalies and management alternatives are discussed.

Reappraisal of ruptured uterus in an urban tertiary center in the Niger-delta region of Nigeria.

OBJECTIVE: To determine the incidence of ruptured uterus as well as the clinical profile and management options in a tertiary hospital setting. METHODS: Thirty-three cases of ruptured uterus managed at University of Benin Teaching Hospital (UBTH) from 1 January 2003 to 31 December 2007 were identified and retrospectively studied. RESULTS: The incidence of ruptured uterus was 4.2 per 1000 deliveries (0.4%). Majority (87.9%) of the patients were unbooked. Injudicious use of oxytocics (63.7%) and prolonged obstructed labor (60.6%) were the main associated risk factors. All 33 patients had laparotomy and 51.2% had repair of the uterine rupture only. The type of surgery performed was influenced by the site and extent of rupture. There were two cases of maternal deaths in this study, giving a case fatality rate of 6.1%. CONCLUSION: Rupture of the gravid uterus is still a problem in Nigeria. A proactive approach to preventing prolonged obstructed labor and curbing the injudicious use of oxytocics through education and utilization of modern antenatal and intrapartum care is advocated.

Ruptured uterus.

Uterine rupture, an important cause of maternal and fetal mortality, is still occasionally seen in our region. In this study we reviewed 41 cases of uterine rupture encountered between the years 1983 and 1988, in a total of 3962 hospital deliveries with a frequency of 1 in 96.6 deliveries. Sixteen cases (39.0%) were over 35 years old. Twenty-five patients (60.9%) were grand multiparous (more than five pregnancies). There were no uterine ruptures in primigravid women. Ruptures were mostly (75.6%) due to cephalopelvic disproportion. Subtotal hysterectomy was the first choice of management for 35 cases. The maternal mortality rate was 7.3% while fetal mortality was 82.9%. Midwife education, regular antenatal care and hospital deliveries are important factors in prevention of this obstetric hazard.